Wilkinson et al. Respond to “Latent Transition Analyses in Clinical Cohorts”

Recent evolutions in human immunodeficiency virus (HIV) prevention mean that epidemiologists face considerable challenges in monitoring and understanding HIV risk behavior through routine surveillance. For example, the arrival of HIV preexposure prophylaxis (use of antiretroviral therapy by HIV-negative individuals to prevent HIV infection) means that traditional indicators such as condomless sex no longer necessarily represent “risk” (1). While sentinel surveillance can efficiently collate data from key risk populations (2), ongoing refinements to the collection and analysis of surveillance data are needed to inform contemporary public health responses to HIV. Read the full response here.