An ARC-funded project has commenced at UNSW to understand the molecular evolution of pathogens in terms of their natural history. The postdoctoral research associate will work with A/Prof Mark Tanaka to model pathogen evolution integrating the processes of mutation and within host dynamics with epidemiological dynamics. Our objective is to produce a closer alignment between mechanistic models that incorporate the ecology and epidemiology of microorganisms on one hand and genomic data on the other. We will use our models to analyse the accumulation of drug resistance, patterns of non-synonymous variation throughout the genome, and genetic interactions. The successful candidate will work within the Tanaka research group, and work closely and cooperatively with the research group of A/Prof Ruiting Lan.
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